Game ID: 22500048
Indiana Pacers @ Cleveland Cavaliers
Friday, November 21, 2025 at 7:00 PM ET
Rocket Arena, Cleveland, OH
Q1 Q2 Q3 Q4 Final
CLE 33 29 38 20 120IND 31 24 26 28 109
CLE vs IND ScoutingCLE vs IND Scouting
Welcome to the scouting desk. The coffee is cold, the film is play-by-play, and somebody has to explain what happened.
Every game has a hinge — a stretch where it was decided, usually while everyone was watching something else. Start where the evidence lives: the Lineups' face-offs say which five actually won their minutes; the Possessions ledger says who ran ahead of the night's own pace; the Shot Chart says where the points really came from, which is rarely where the highlights were. When all three agree, that is the story. When they don't — that is why this desk has a chair.
CLE availability going into 11/13 · back-to-backBACK Allen back 11/05 after 2, 26 min since (93% of 28)
BACK Merrill back 11/05 after 3, 25 min since (101% of 25)
BACK Tomlin back 11/05 after 7, 8 min since (57% of 14)
BACK Nance Jr. back 11/12 after 2, 19 min since (158% of 12)
BACK Bryant back 11/12 after 2, 13 min since (114% of 11)
CLE availability going into 11/15 · 1 day's restOUT Garland missed 2 since 11/12, out tonight
OUT Tyson missed 2 since 11/12, out tonight
BACK Tomlin back 11/12 after 2, 20 min since (136% of 14)
BACK Nance Jr. back 11/12 after 2, 13 min since (107% of 12)
BACK Bryant back 11/12 after 2, 10 min since (88% of 11)
NEW Proctor 10 to 16 min over the last 4
CLE availability going into 11/17 · 1 day's restOUT Garland missed 3 since 11/12, out tonight
OUT Tyson missed 3 since 11/12, out tonight
BACK Tomlin back 11/12 after 2, 19 min since (132% of 14)
BACK Nance Jr. back 11/12 after 2, 10 min since (84% of 12)
BACK Bryant back 11/12 after 2, 10 min since (88% of 11)
CLE availability going into 11/19 · 1 day's restOUT Garland missed 4 since 11/12, out tonight
OUT Tyson missed 4 since 11/12, out tonight
BACK Tomlin back 11/12 after 2, 17 min since (120% of 14)
BACK Nance Jr. back 11/12 after 2, 10 min since (84% of 12)
BACK Bryant back 11/12 after 2, 9 min since (79% of 11)
CLE availability going into 11/21 · 1 day's restOUT Garland missed 5 since 11/12, returns tonight: 27 min (87% of 30)
OUT Tyson missed 5 since 11/12, returns tonight: 27 min (112% of 24)
OUT Nance Jr. missed 2 since 11/17, returns tonight: 19 min (156% of 12)
BACK Tomlin back 11/12 after 2, 18 min since (123% of 14)
BACK Bryant back 11/12 after 2, 8 min since (68% of 11)
NEW Porter Jr. 16 to 23 min over the last 5
CLE availability going into 11/23 · 1 day's restOUT Merrill missed 2 since 11/19, out tonight
BACK Garland back 11/21 after 5, 27 min since (87% of 30)
BACK Tyson back 11/21 after 5, 27 min since (112% of 24)
BACK Nance Jr. back 11/21 after 2, 19 min since (156% of 12)
CLE availability going into 11/24 · back-to-backOUT Allen missed 2 since 11/21, out tonight
OUT Merrill missed 3 since 11/19, out tonight
BACK Garland back 11/21 after 5, 28 min since (92% of 30)
BACK Tyson back 11/21 after 5, 25 min since (104% of 24)
BACK Nance Jr. back 11/21 after 2, 16 min since (129% of 12)
CLE availability going into 11/28 · 3 days' restOUT Allen missed 3 since 11/21, returns tonight: 28 min (101% of 28)
OUT Merrill missed 4 since 11/19, out tonight
OUT Porter Jr. missed 2 since 11/23, out tonight
BACK Garland back 11/21 after 5, 28 min since (92% of 30)
BACK Tyson back 11/21 after 5, 28 min since (116% of 24)
BACK Nance Jr. back 11/21 after 2, 17 min since (135% of 12)
NEW Ball 21 to 27 min over the last 4
NEW Tomlin 14 to 19 min over the last 5
CLE availability going into 11/30 · 1 day's restOUT Merrill missed 5 since 11/19, out tonight
OUT Porter Jr. missed 3 since 11/23, returns tonight: 11 min (65% of 16)
BACK Garland back 11/21 after 5, 30 min since (97% of 30)
BACK Allen back 11/28 after 3, 28 min since (101% of 28)
BACK Tyson back 11/21 after 5, 26 min since (109% of 24)
BACK Nance Jr. back 11/21 after 2, 15 min since (121% of 12)
IND availability going into 11/13 · 1 day's restOUT Mathurin missed 9 since 10/26, out tonight
OUT Furphy missed 4 since 11/05, out tonight
OUT Que. Jackson missed 4 since 11/05, out tonight
OUT Toppin missed 8 since 10/29, out tonight
OUT Wiseman missed 9 since 10/26, out tonight
BACK Nembhard back 11/08 after 7, 31 min since (98% of 31)
NEW Isa. Jackson 17 to 22 min over the last 5
NEW Morris 11 to 16 min over the last 3
IND availability going into 11/15 · 1 day's restOUT Mathurin missed 10 since 10/26, out tonight
OUT Furphy missed 5 since 11/05, out tonight
OUT Que. Jackson missed 5 since 11/05, out tonight
OUT Toppin missed 9 since 10/29, out tonight
OUT Wiseman missed 10 since 10/26, out tonight
BACK Nembhard back 11/08 after 7, 30 min since (96% of 31)
NEW Robinson-Earl 18 to 25 min over the last 5
NEW Bradley 11 to 16 min over the last 5
IND availability going into 11/17 · 1 day's restOUT Mathurin missed 11 since 10/26, returns tonight: 25 min (79% of 32)
OUT Furphy missed 6 since 11/05, out tonight
OUT Que. Jackson missed 6 since 11/05, out tonight
OUT Toppin missed 10 since 10/29, out tonight
OUT Wiseman missed 11 since 10/26, out tonight
BACK Nembhard back 11/08 after 7, 30 min since (97% of 31)
NEW Robinson-Earl 18 to 26 min over the last 5
NEW Bradley 11 to 18 min over the last 5
IND availability going into 11/19 · 1 day's restOUT Nesmith missed 2 since 11/15, out tonight
OUT Furphy missed 7 since 11/05, out tonight
OUT Que. Jackson missed 7 since 11/05, out tonight
OUT Toppin missed 11 since 10/29, out tonight
OUT Wiseman missed 12 since 10/26, out tonight
BACK Mathurin back 11/17 after 11, 25 min since (79% of 32)
NEW Robinson-Earl 18 to 26 min over the last 5
NEW Bradley 11 to 18 min over the last 5
IND availability going into 11/21 · 1 day's restOUT Nesmith missed 3 since 11/15, out tonight
OUT Furphy missed 8 since 11/05, out tonight
OUT Que. Jackson missed 8 since 11/05, out tonight
OUT Toppin missed 12 since 10/29, out tonight
OUT Wiseman missed 13 since 10/26, out tonight
OUT Dennis missed 2 since 11/17, returns tonight: 1 min (9% of 13)
BACK Mathurin back 11/17 after 11, 30 min since (93% of 32)
NEW Robinson-Earl 18 to 23 min over the last 5
IND availability going into 11/24 · 2 days' restOUT Nesmith missed 4 since 11/15, out tonight
OUT Furphy missed 9 since 11/05, out tonight
OUT Que. Jackson missed 9 since 11/05, out tonight
OUT Toppin missed 13 since 10/29, out tonight
OUT Wiseman missed 14 since 10/26, out tonight
BACK Mathurin back 11/17 after 11, 32 min since (101% of 32)
BACK Dennis back 11/21 after 2, 1 min since (9% of 13)
IND availability going into 11/26 · 1 day's restOUT Nesmith missed 5 since 11/15, out tonight
OUT Furphy missed 10 since 11/05, out tonight
OUT Que. Jackson missed 10 since 11/05, out tonight
OUT Toppin missed 14 since 10/29, out tonight
OUT Wiseman missed 15 since 10/26, out tonight
BACK Mathurin back 11/17 after 11, 31 min since (98% of 32)
BACK Dennis back 11/21 after 2, 1 min since (9% of 13)
IND availability going into 11/28 · 1 day's restOUT Nesmith missed 6 since 11/15, out tonight
OUT Furphy missed 11 since 11/05, out tonight
OUT Que. Jackson missed 11 since 11/05, out tonight
OUT Toppin missed 15 since 10/29, out tonight
OUT Wiseman missed 16 since 10/26, out tonight
OUT Peter missed 2 since 11/24, returns tonight: 6 min (45% of 13)
OUT Dennis missed 2 since 11/24, returns tonight: 6 min (45% of 13)
BACK Mathurin back 11/17 after 11, 32 min since (100% of 32)
NEW Sheppard 21 to 27 min over the last 5
IND availability going into 11/29 · back-to-backOUT Nesmith missed 7 since 11/15, out tonight
OUT Furphy missed 12 since 11/05, out tonight
OUT Que. Jackson missed 12 since 11/05, out tonight
OUT Toppin missed 16 since 10/29, out tonight
OUT Wiseman missed 17 since 10/26, out tonight
BACK Peter back 11/28 after 2, 6 min since (45% of 13)
BACK Dennis back 11/21 after 2, 4 min since (27% of 13)
NEW Sheppard 21 to 27 min over the last 5
I Know — the desk, before tip-off
Written before tip-off, from the five games each side brought in.
Cleveland comes in 3-2 over its last five, scoring 115 a night and allowing 112, shooting 47 percent and 32 from three, 28 free throws a game; Mitchell at 30 and Hunter at 16 a game. Without Garland (5 straight), Tyson (5 straight). One day's rest. Indiana comes in 1-4 over its last five, scoring 115 a night and allowing 132, shooting 44 percent and 33 from three, 31 free throws a game; Siakam at 25 and Nembhard at 20 a game. It has lost the glass by 5 a night. Without Nesmith (3 straight), Furphy (8 straight), Que. Jackson (8 straight). One day's rest.
So: Cleveland wins, and the game turns on the defense, Cleveland allowing 112 a night to Indiana's 132 and the glass, where Cleveland has been plus-0 a night and Indiana minus-5. Call it Cleveland 124, Indiana 112, Cleveland by 12.
11/13 vs TOR 113-126 — CLE notes
CLE lost 113-126. CLE shot 45% (41 of 91) to TOR's 56%, 10 of 41 from three, and went to the line 26 times to TOR's 17 — 21 points from the stripe to their 16. Mitchell led with 31 (7 of 18, 2 of 9 from three, 15 of 17 at the line); Tomlin added 18, Hunter 16. Q3 was theirs, 31-23, the deficit cut from 13 to 5, but the other 3 periods went 103-82 against them. They led by as many as 10. Mitchell's -18 in 36 minutes was the worst on the floor.
11/15 vs MEM 108-100 — CLE notes
CLE won 108-100. CLE shot 46% (38 of 83) to MEM's 36%, 13 of 40 from three, and got to the line 29 times to MEM's 40. CLE turned it over 20 times to MEM's 15, and MEM turned those into 9 steals. Mitchell led with 30 (10 of 21, 4 of 13 from three, 6 of 9 at the line); Mobley added 22, Allen 16. The hinge was Q4, 32-16: CLE came in trailing by 8 and left it ahead by 8. CLE trailed 54-61 at the half and won the second half 54-39. Wade was the night's best plus/minus at +22.
11/17 vs MIL 118-106 — CLE notes
CLE won 118-106. CLE shot 56% (44 of 79) to MIL's 42%, 15 of 35 from three, and went to the line 21 times to MIL's 15 — 15 points from the stripe to their 11. The glass went 45-34 for them. Mitchell led with 37 (14 of 22, 4 of 8 from three, 5 of 7 at the line); Merrill added 20, Mobley 14. The hinge was Q2, 33-24: CLE came in trailing by 7 and left it ahead by 2. Wade was the night's best plus/minus at +14.
11/19 vs HOU 104-114 — CLE notes
CLE lost 104-114. CLE shot 44% (36 of 81) to HOU's 46%, 12 of 39 from three. The glass went 39-51 against them. Hunter led with 25 (6 of 11, 5 of 8 from three, 8 of 8 at the line); Mitchell added 21, Mobley 18. Q3 was theirs, 30-17, the deficit cut from 17 to 4, but the other 3 periods went 97-74 against them. Mitchell's -18 in 34 minutes was the worst on the floor.
11/21 vs IND 120-109 — CLE notes
CLE won 120-109. CLE shot 48% (43 of 89) to IND's 42%, 13 of 35 from three. Mitchell led with 32 (11 of 22, 4 of 11 from three, 6 of 8 at the line); Mobley added 22, Hunter 20. The hinge was Q3, 38-26: a lead of 7 became 19, and the lead reached 22. Hunter was the night's best plus/minus at +19.
11/23 vs LAC — I Know, the desk before tip-off
Written before tip-off, from the five games each side brought in.
Cleveland comes in 3-2 over its last five, scoring 113 a night and allowing 111, shooting 48 percent and 33 from three, 27 free throws a game; Mitchell at 30 and Mobley at 17 a game. Without Merrill (2 straight). One day's rest. The Clippers come in 2-3 over their last five, scoring 118 a night and allowing 121, shooting 45 percent and 37 from three, 27 free throws a game; Harden at 38 and Zubac at 18 a game. Without Leonard (10 straight), Jones Jr. (3 straight), Miller (3 straight). Second night of a back-to-back.
So: Cleveland wins, and the game turns on the defense, Cleveland allowing 111 a night to the Clippers' 121 and the glass, where Cleveland has been plus-1 a night and the Clippers minus-3. Call it Cleveland 120, the Clippers 112.
11/24 @ TOR — I Know, the desk before tip-off
Written before tip-off, from the five games each side brought in.
Toronto comes in 5-0 over its last five, scoring 124 a night and allowing 110, shooting 53 percent and 40 from three, 30 free throws a game; Ingram at 21 and Barrett at 20 a game. That is 5 straight wins. Second night of a back-to-back. Cleveland comes in 4-1 over its last five, scoring 114 a night and allowing 107, shooting 49 percent and 36 from three, 26 free throws a game; Mitchell at 31 and Mobley at 19 a game. Without Allen (2 straight), Merrill (3 straight). Second night of a back-to-back.
So: Toronto wins, and the game turns on the arc, Toronto at 40 percent from three to Cleveland's 36. Call it Toronto 118, Cleveland 113.
11/28 @ ATL — I Know, the desk before tip-off
Written before tip-off, from the five games each side brought in.
Atlanta comes in 2-3 over its last five, scoring 116 a night and allowing 119, shooting 49 percent and 39 from three, 16 free throws a game; Porziņģis at 23 and Johnson at 21 a game. Without Young (14 straight). 2 days' rest. Cleveland comes in 3-2 over its last five, scoring 112 a night and allowing 109, shooting 48 percent and 35 from three, 23 free throws a game; Mitchell at 29 and Hunter at 18 a game. Without Allen (3 straight), Merrill (4 straight), Porter Jr. (2 straight). 3 days' rest.
So: Atlanta wins, and the game turns on the defense, Cleveland allowing 109 a night to Atlanta's 119 and the line, where Cleveland takes 23 free throws a game to Atlanta's 16. Call it Atlanta 116, Cleveland 115, Cleveland keeping it close.
11/30 vs BOS — I Know, the desk before tip-off
Written before tip-off, from the five games each side brought in.
Cleveland comes in 2-3 over its last five, scoring 113 a night and allowing 114, shooting 46 percent and 35 from three, 22 free throws a game; Mitchell at 30 and Hunter at 20 a game. Without Merrill (5 straight), Porter Jr. (3 straight). One day's rest. Boston comes in 3-2 over its last five, scoring 118 a night and allowing 115, shooting 49 percent and 41 from three, 20 free throws a game; Brown at 33 and White at 16 a game. Second night of a back-to-back.
So: Cleveland wins, and the game turns on the arc, Boston at 41 percent from three to Cleveland's 35. Call it Cleveland 116, Boston 114, Boston keeping it close.
11/13 @ PHX 98-133 — IND notes
IND lost 98-133. IND shot 36% (32 of 88) to PHX's 58%, 7 of 25 from three. Nembhard led with 21 (5 of 15, 1 of 5 from three, 10 of 11 at the line); Siakam added 19, Nesmith 10. Q3 was theirs, 32-36, but the other 3 periods went 97-66 against them. McConnell's -30 in 15 minutes was the worst on the floor.
11/15 vs TOR 111-129 — IND notes
IND lost 111-129. IND shot 43% (37 of 87) to TOR's 55%, 15 of 43 from three, and got to the line 27 times to TOR's 42. Siakam led with 30 (10 of 19, 5 of 10 from three, 5 of 6 at the line); Nembhard added 22. Q4 was theirs, 26-28, but the other 3 periods went 101-85 against them. They led by as many as 10. Sheppard's -15 in 20 minutes was the worst on the floor.
11/17 @ DET 112-127 — IND notes
IND lost 112-127. IND shot 42% (35 of 84) to DET's 55%, 9 of 31 from three, and went to the line 45 times to DET's 30 — 33 points from the stripe to their 22. IND turned it over 21 times to DET's 16, and DET turned those into 9 steals. Siakam led with 29 (8 of 17, 3 of 8 from three, 10 of 12 at the line); Mathurin added 25, Jackson 16. Q4 was theirs, 37-34, the deficit cut from 18 to 15, but the other 3 periods went 93-75 against them. Siakam's -29 in 34 minutes was the worst on the floor.
11/19 vs CHA 127-118 — IND notes
IND won 127-118. IND shot 54% (46 of 85) to CHA's 40%, 16 of 38 from three. Mathurin led with 24 (7 of 13, 2 of 5 from three, 8 of 9 at the line); Siakam added 22, Huff 20. The hinge was Q2, 32-21: a lead of 5 became 16, and the lead reached 24. Siakam was the night's best plus/minus at +25.
11/21 @ CLE 109-120 — IND notes
IND lost 109-120. IND shot 42% (37 of 88) to CLE's 48%, 11 of 37 from three. Nembhard led with 32 (11 of 20, 3 of 5 from three, 7 of 7 at the line); Siakam added 26, Mathurin 21. Q4 was theirs, 28-20, the deficit cut from 19 to 11, but the other 3 periods went 100-81 against them. Sheppard's -16 in 25 minutes was the worst on the floor.
11/24 vs DET — I Know, the desk before tip-off
Written before tip-off, from the five games each side brought in.
Indiana comes in 1-4 over its last five, scoring 111 a night and allowing 125, shooting 43 percent and 33 from three, 30 free throws a game; Siakam at 25 and Mathurin at 23 a game. It has lost the glass by 4 a night. Without Nesmith (4 straight), Furphy (9 straight), Que. Jackson (9 straight). 2 days' rest. Detroit comes in 5-0 over its last five, scoring 123 a night and allowing 112, shooting 54 percent and 39 from three, 22 free throws a game; Duren at 25 and Jenkins at 17 a game. That is 5 straight wins. One day's rest.
So: Detroit wins, on the road, and the game turns on the defense, Detroit allowing 112 a night to Indiana's 125 and the line, where Indiana takes 30 free throws a game to Detroit's 22. Call it Detroit 121, Indiana 113.
11/26 @ TOR — I Know, the desk before tip-off
Written before tip-off, from the five games each side brought in.
Toronto comes in 5-0 over its last five, scoring 120 a night and allowing 108, shooting 51 percent and 41 from three, 25 free throws a game; Ingram at 25 and Barrett at 20 a game. That is 5 straight wins. One day's rest. Indiana comes in 1-4 over its last five, scoring 115 a night and allowing 123, shooting 46 percent and 36 from three, 31 free throws a game; Siakam at 26 and Mathurin at 21 a game. It has lost the glass by 7 a night. Without Nesmith (5 straight), Furphy (10 straight), Que. Jackson (10 straight). One day's rest.
So: Toronto wins, and the game turns on the defense, Toronto allowing 108 a night to Indiana's 123 and the glass, where Toronto has been plus-2 a night and Indiana minus-7. Call it Toronto 123, Indiana 110, Toronto by 13.
11/28 vs WAS — I Know, the desk before tip-off
Written before tip-off, from the five games each side brought in.
Indiana comes in 1-4 over its last five, scoring 112 a night and allowing 117, shooting 46 percent and 35 from three, 30 free throws a game; Siakam at 22 and Mathurin at 20 a game. That is 3 straight losses. It has lost the glass by 7 a night. Without Nesmith (6 straight), Furphy (11 straight), Que. Jackson (11 straight). One day's rest. Washington comes in 1-4 over its last five, scoring 115 a night and allowing 125, shooting 48 percent and 40 from three, 21 free throws a game; McCollum at 23 and George at 18 a game. It has lost the glass by 9 a night. Without Johnson (2 straight), Bagley III (3 straight), Gill (2 straight). 2 days' rest.
So: Indiana wins, and the game turns on the line, where Indiana takes 30 free throws a game to Washington's 21 and the defense, Indiana allowing 117 a night to Washington's 125. Call it Indiana 120, Washington 116, Washington keeping it close.
11/29 vs CHI — I Know, the desk before tip-off
Written before tip-off, from the five games each side brought in.
Indiana comes in 2-3 over its last five, scoring 113 a night and allowing 109, shooting 48 percent and 37 from three, 24 free throws a game; Siakam at 21 and Mathurin at 19 a game. It has lost the glass by 5 a night. Without Nesmith (7 straight), Furphy (12 straight), Que. Jackson (12 straight). Second night of a back-to-back. Chicago comes in 2-3 over its last five, scoring 119 a night and allowing 130, shooting 46 percent and 33 from three, 25 free throws a game; White at 24 and Vučević at 18 a game. It has lost the glass by 13 a night. Without Okoro (3 straight). Second night of a back-to-back.
So: Indiana wins, and the game turns on the defense, Indiana allowing 109 a night to Chicago's 130 and the glass, where Indiana has been minus-5 a night and Chicago minus-13. Call it Indiana 121, Chicago 115.
Who is who
the initials in the Players column
CLECP C. Porter Jr.
DG D. Garland
DH D. Hunter
DM D. Mitchell
DW D. Wade
EM E. Mobley
JT J. Tyson
LB L. Ball
LN L. Nance Jr.
NT N. Tomlin
TB T. Bryant
TP T. Proctor
INDAN A. Nembhard
BM B. Mathurin
BS B. Sheppard
GM G. Mathews
IJ I. Jackson
JH J. Huff
JR J. Robinson-Earl
JW J. Walker
PS P. Siakam
TB T. Bradley
TM T. McConnell
TP T. Peter
CLE/IND the team itself, not a player
-- the feed named nobody
What
What happened
the codes in the Events column
M2 / M3 made 2 / made 3
X2 / X3 missed 2 / missed 3
FT / X1 free throw made / missed
AST assist
OR / DR offensive / defensive rebound
STL steal
BLK block
TO turnover
FL foul
OF offensive foul — ends the possession
VIOL violation
JUMP jump ball
TM timeout
IR instant replay
HE heave at the buzzer, filed to the team
END the clock ran out, ball in hand
Where
Where a shot came from
the middle field of M3.LW.25
RM at the rim inside 4 ft
RC right corner
RW right wing
SO straight on
LW left wing
LC left corner
M3.LW.25 made 3, left wing, 25 ft
X2.RM.01 missed 2, at the rim, 1 ft
When
When it happened
the Offset column
one number per event, in the Events order:
whole seconds from the start of the
possession to that event
Events FL X3.RC.23 OR M2.RM.01
Offset 0 18 22 24
the foul opens the possession at 0s;
the putback ends it at 24s, which is
the possession's own Dur
Mitchell scores 32, Garland adds 20 in return as Cavaliers beat Pacers 120-109 in NBA Cup
CLEVELAND -- — Donovan Mitchell scored 32 points, Darius Garland had 20 in his return to Cleveland's lineup and the Cavaliers pulled away in the second half for a 120-109 victory over the Indiana Pacers in an NBA Cup game on Friday night.
It was the first meeting between the teams since the Pacers eliminated the top-seeded Cavaliers in five games in last season’s Eastern Conference semifinals.
Evan Mobley added 22 points and 12 rebounds for the Cavaliers, who improved to 2-1 in East Group A.
Andrew Nembhard had a career-high 32 points for injury-plagued Indiana, which fell to 0-2 in group play. Pascal Siakham added 26 points and nine rebounds and Bennedict Mathurin scored 21 points.
The NBA finalists from a year ago are 2-14 and missing six players. Indiana has dropped nine of its last 10.
Garland missed five games due to a contusion on the left big toe that he had surgically repaired in June.
The two-time All-Star point guard played 26 minutes and scored 18 points in the first half. He finished 5 for 12 from the field, including three 3-pointers, and made all seven of his free throws.
The Cavaliers led 62-55 at halftime before they went on a 21-9 run over a four-minute span in the third quarter to take control. Jalen Tyson scored eight of his 14 points during the spurt, which pushed their advantage up to 16 midway through the quarter.
Cleveland's largest lead was 103-81 on Mitchell's pullup 3-point early in the fourth quarter. It was the ninth time in 15 games this season the All-Star guard has scored at least 30 points.
Indiana made a 16-4 run to get within 10 with five minutes remaining, but could not draw closer.